Class: AdverseOutcomePathway

A sequence of causally linked events at different levels of biological organization that lead from exposure to adverse health outcomes

URI: exposome_schema:AdverseOutcomePathway

classDiagram class AdverseOutcomePathway click AdverseOutcomePathway href "../AdverseOutcomePathway/" NamedThing <|-- AdverseOutcomePathway click NamedThing href "../NamedThing/" AdverseOutcomePathway : adverse_outcome AdverseOutcomePathway --> "0..1" AdverseOutcome : adverse_outcome click AdverseOutcome href "../AdverseOutcome/" AdverseOutcomePathway : aopwiki_id AdverseOutcomePathway : category AdverseOutcomePathway : description AdverseOutcomePathway : id AdverseOutcomePathway : key_event_relationships AdverseOutcomePathway --> "*" KeyEventRelationship : key_event_relationships click KeyEventRelationship href "../KeyEventRelationship/" AdverseOutcomePathway : key_events AdverseOutcomePathway --> "*" KeyEvent : key_events click KeyEvent href "../KeyEvent/" AdverseOutcomePathway : molecular_initiating_event AdverseOutcomePathway --> "0..1" MolecularInitiatingEvent : molecular_initiating_event click MolecularInitiatingEvent href "../MolecularInitiatingEvent/" AdverseOutcomePathway : name AdverseOutcomePathway : stressors AdverseOutcomePathway --> "*" ChemicalEntity : stressors click ChemicalEntity href "../ChemicalEntity/" AdverseOutcomePathway : xref

Inheritance

NamedThing
- AdverseOutcomePathway

Slots

Name	Cardinality and Range	Description	Inheritance
aopwiki_id	0..1 String	AOP Wiki identifier	direct
molecular_initiating_event	0..1 MolecularInitiatingEvent	The molecular initiating event of an AOP	direct
key_events	* KeyEvent	Key events in an AOP	direct
key_event_relationships	* KeyEventRelationship	Relationships between key events	direct
adverse_outcome	0..1 AdverseOutcome	The adverse outcome of an AOP	direct
stressors	* ChemicalEntity	Chemical stressors that trigger the AOP	direct
id	1 Uriorcurie	A unique identifier for a thing	NamedThing
name	0..1 String	A human-readable name for a thing	NamedThing
description	0..1 String	A human-readable description for a thing	NamedThing
category	* String	A category or type for a thing	NamedThing
xref	* Uriorcurie	External database cross-references	NamedThing

Usages

used by	used in	type	used
ExposomeDatabase	adverse_outcome_pathways	range	AdverseOutcomePathway

Identifier and Mapping Information

Schema Source

from schema: https://w3id.org/diatomsRcool/exposome-schema

Mappings

Mapping Type	Mapped Value
self	exposome_schema:AdverseOutcomePathway
native	exposome_schema:AdverseOutcomePathway

LinkML Source

Direct

name: AdverseOutcomePathway
description: A sequence of causally linked events at different levels of biological
  organization that lead from exposure to adverse health outcomes
from_schema: https://w3id.org/diatomsRcool/exposome-schema
is_a: NamedThing
slots:
- aopwiki_id
- molecular_initiating_event
- key_events
- key_event_relationships
- adverse_outcome
- stressors

Induced

name: AdverseOutcomePathway
description: A sequence of causally linked events at different levels of biological
  organization that lead from exposure to adverse health outcomes
from_schema: https://w3id.org/diatomsRcool/exposome-schema
is_a: NamedThing
attributes:
  aopwiki_id:
    name: aopwiki_id
    description: AOP Wiki identifier
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    alias: aopwiki_id
    owner: AdverseOutcomePathway
    domain_of:
    - AdverseOutcomePathway
    range: string
  molecular_initiating_event:
    name: molecular_initiating_event
    description: The molecular initiating event of an AOP
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    alias: molecular_initiating_event
    owner: AdverseOutcomePathway
    domain_of:
    - AdverseOutcomePathway
    range: MolecularInitiatingEvent
  key_events:
    name: key_events
    description: Key events in an AOP
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    alias: key_events
    owner: AdverseOutcomePathway
    domain_of:
    - AdverseOutcomePathway
    range: KeyEvent
    multivalued: true
  key_event_relationships:
    name: key_event_relationships
    description: Relationships between key events
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    alias: key_event_relationships
    owner: AdverseOutcomePathway
    domain_of:
    - AdverseOutcomePathway
    range: KeyEventRelationship
    multivalued: true
  adverse_outcome:
    name: adverse_outcome
    description: The adverse outcome of an AOP
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    alias: adverse_outcome
    owner: AdverseOutcomePathway
    domain_of:
    - AdverseOutcomePathway
    range: AdverseOutcome
  stressors:
    name: stressors
    description: Chemical stressors that trigger the AOP
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    alias: stressors
    owner: AdverseOutcomePathway
    domain_of:
    - AdverseOutcomePathway
    range: ChemicalEntity
    multivalued: true
  id:
    name: id
    description: A unique identifier for a thing
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    slot_uri: schema:identifier
    identifier: true
    alias: id
    owner: AdverseOutcomePathway
    domain_of:
    - NamedThing
    range: uriorcurie
    required: true
  name:
    name: name
    description: A human-readable name for a thing
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    slot_uri: schema:name
    alias: name
    owner: AdverseOutcomePathway
    domain_of:
    - NamedThing
    range: string
  description:
    name: description
    description: A human-readable description for a thing
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    slot_uri: schema:description
    alias: description
    owner: AdverseOutcomePathway
    domain_of:
    - NamedThing
    range: string
  category:
    name: category
    description: A category or type for a thing
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    alias: category
    owner: AdverseOutcomePathway
    domain_of:
    - NamedThing
    range: string
    multivalued: true
  xref:
    name: xref
    description: External database cross-references
    from_schema: https://w3id.org/diatomsRcool/exposome-schema
    rank: 1000
    alias: xref
    owner: AdverseOutcomePathway
    domain_of:
    - NamedThing
    range: uriorcurie
    multivalued: true