Class: KeRelationship

A scientifically-based relationship that connects one key event to another, defines a causal and predictive relationship between the upstream and downstream event, and thereby facilitates inference or extrapolation of the state of the downstream key event from the known, measured, or predicted state of the upstream key event.

URI: http://example.org/aopwiki-emod/KeRelationship

classDiagram class KeRelationship click KeRelationship href "../KeRelationship/" KeRelationship : aops KeRelationship --> "*" AopToKeRelationship : aops click AopToKeRelationship href "../AopToKeRelationship/" KeRelationship : assays KeRelationship --> "*" Assay : assays click Assay href "../Assay/" KeRelationship : biological_plausibility KeRelationship : completion_score KeRelationship : created_at KeRelationship : downstream_event_id KeRelationship --> "0..1" Event : downstream_event_id click Event href "../Event/" KeRelationship : empirical_support KeRelationship : evidence_collection_strategy KeRelationship : has_tabulated_evidence KeRelationship : how_it_works KeRelationship : id KeRelationship : known_loops KeRelationship : life_stages KeRelationship --> "*" KeRelationshipToLifeStage : life_stages click KeRelationshipToLifeStage href "../KeRelationshipToLifeStage/" KeRelationship : modulating_factors KeRelationship : quantitative_understanding KeRelationship : references KeRelationship : response_relationship KeRelationship : sexes KeRelationship --> "*" KeRelationshipToSex : sexes click KeRelationshipToSex href "../KeRelationshipToSex/" KeRelationship : taxon_evidence KeRelationship : taxons KeRelationship --> "*" KeRelationshipToTaxon : taxons click KeRelationshipToTaxon href "../KeRelationshipToTaxon/" KeRelationship : time_scale KeRelationship : uncertainties KeRelationship : updated_at KeRelationship : upstream_event_id KeRelationship --> "0..1" Event : upstream_event_id click Event href "../Event/" KeRelationship : weight_of_evidence

Slots

Name	Cardinality and Range	Description	Inheritance
created_at	0..1 Datetime	Timestamp of when the record was created	direct
updated_at	0..1 Datetime	Timestamp of when the record was last updated	direct
id	1 Integer		direct
upstream_event_id	0..1 Event		direct
downstream_event_id	0..1 Event		direct
how_it_works	0..1 String		direct
biological_plausibility	0..1 String		direct
empirical_support	0..1 String		direct
uncertainties	0..1 String		direct
quantitative_understanding	0..1 String		direct
taxon_evidence	0..1 String		direct
weight_of_evidence	0..1 String		direct
response_relationship	0..1 String		direct
time_scale	0..1 String		direct
modulating_factors	0..1 String		direct
known_loops	0..1 String		direct
evidence_collection_strategy	0..1 String		direct
references	0..1 String		direct
completion_score	0..1 Float		direct
has_tabulated_evidence	0..1 Boolean		direct
assays	* Assay	Assays that measure both the upstream and the downstream Event of this relati...	direct
aops	* AopToKeRelationship		direct
taxons	* KeRelationshipToTaxon		direct
sexes	* KeRelationshipToSex		direct
life_stages	* KeRelationshipToLifeStage		direct

Usages

used by	used in	type	used
Assay	ke_relationships	range	KeRelationship
Evidence	relationship_id	range	KeRelationship
AopToKeRelationship	relationship_id	range	KeRelationship
KeRelationshipToLifeStage	relationship_id	range	KeRelationship
KeRelationshipToSex	relationship_id	range	KeRelationship
KeRelationshipToTaxon	relationship_id	range	KeRelationship

Identifier and Mapping Information

Schema Source

from schema: http://example.org/aopwiki-emod

Mappings

Mapping Type	Mapped Value
self	http://example.org/aopwiki-emod/KeRelationship
native	http://example.org/aopwiki-emod/KeRelationship

LinkML Source

Direct

name: KeRelationship
description: A scientifically-based relationship that connects one key event to another,
  defines a causal and predictive relationship between the upstream and downstream
  event, and thereby facilitates inference or extrapolation of the state of the downstream
  key event from the known, measured, or predicted state of the upstream key event.
from_schema: http://example.org/aopwiki-emod
slots:
- created_at
- updated_at
attributes:
  id:
    name: id
    from_schema: http://example.org/aopwiki-emod
    identifier: true
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Assay
    - Observation
    - Evidence
    - Stressor
    - Citation
    - BiologicalAction
    - BiologicalObject
    - BiologicalProcess
    - LevelOfBiologicalOrganization
    - AopToEvent
    - AopToLifeStage
    - AopToKeRelationship
    - AopToSex
    - AopToPrototypicalStressor
    - AopToTaxon
    - AssignedLicense
    - BioTargetFamily
    - CellTerm
    - ConfidenceLevel
    - Directness
    - EventToLifeStage
    - EventToSex
    - EventToTaxon
    - ExperimentSetup
    - ExperimentType
    - Handbook
    - HarmonizedAop
    - HarmonizedEvent
    - License
    - LifeStageTerm
    - OecdStatus
    - OrganTerm
    - KeRelationshipToLifeStage
    - KeRelationshipToSex
    - KeRelationshipToTaxon
    - SexTerm
    - EventComponent
    - TaxonTerm
    - TestGuideline
    - User
    range: integer
    required: true
  upstream_event_id:
    name: upstream_event_id
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
    range: Event
  downstream_event_id:
    name: downstream_event_id
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
    range: Event
  how_it_works:
    name: how_it_works
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Event
    - KeRelationship
  biological_plausibility:
    name: biological_plausibility
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  empirical_support:
    name: empirical_support
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  uncertainties:
    name: uncertainties
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  quantitative_understanding:
    name: quantitative_understanding
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  taxon_evidence:
    name: taxon_evidence
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  weight_of_evidence:
    name: weight_of_evidence
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  response_relationship:
    name: response_relationship
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  time_scale:
    name: time_scale
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  modulating_factors:
    name: modulating_factors
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  known_loops:
    name: known_loops
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  evidence_collection_strategy:
    name: evidence_collection_strategy
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
  references:
    name: references
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Event
    - KeRelationship
  completion_score:
    name: completion_score
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: float
  has_tabulated_evidence:
    name: has_tabulated_evidence
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - KeRelationship
    range: boolean
  assays:
    name: assays
    description: Assays that measure both the upstream and the downstream Event of
      this relationship in the same test system, so that one assay can inform the
      relationship as a single module.
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Citation
    - BioTargetFamily
    - TestGuideline
    range: Assay
    multivalued: true
  aops:
    name: aops
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Event
    - KeRelationship
    - Assay
    - Stressor
    range: AopToKeRelationship
    multivalued: true
    inlined: true
    inlined_as_list: true
  taxons:
    name: taxons
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: KeRelationshipToTaxon
    multivalued: true
    inlined: true
    inlined_as_list: true
  sexes:
    name: sexes
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: KeRelationshipToSex
    multivalued: true
    inlined: true
    inlined_as_list: true
  life_stages:
    name: life_stages
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: KeRelationshipToLifeStage
    multivalued: true
    inlined: true
    inlined_as_list: true

Induced

name: KeRelationship
description: A scientifically-based relationship that connects one key event to another,
  defines a causal and predictive relationship between the upstream and downstream
  event, and thereby facilitates inference or extrapolation of the state of the downstream
  key event from the known, measured, or predicted state of the upstream key event.
from_schema: http://example.org/aopwiki-emod
attributes:
  id:
    name: id
    from_schema: http://example.org/aopwiki-emod
    identifier: true
    alias: id
    owner: KeRelationship
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Assay
    - Observation
    - Evidence
    - Stressor
    - Citation
    - BiologicalAction
    - BiologicalObject
    - BiologicalProcess
    - LevelOfBiologicalOrganization
    - AopToEvent
    - AopToLifeStage
    - AopToKeRelationship
    - AopToSex
    - AopToPrototypicalStressor
    - AopToTaxon
    - AssignedLicense
    - BioTargetFamily
    - CellTerm
    - ConfidenceLevel
    - Directness
    - EventToLifeStage
    - EventToSex
    - EventToTaxon
    - ExperimentSetup
    - ExperimentType
    - Handbook
    - HarmonizedAop
    - HarmonizedEvent
    - License
    - LifeStageTerm
    - OecdStatus
    - OrganTerm
    - KeRelationshipToLifeStage
    - KeRelationshipToSex
    - KeRelationshipToTaxon
    - SexTerm
    - EventComponent
    - TaxonTerm
    - TestGuideline
    - User
    range: integer
    required: true
  upstream_event_id:
    name: upstream_event_id
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: upstream_event_id
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: Event
  downstream_event_id:
    name: downstream_event_id
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: downstream_event_id
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: Event
  how_it_works:
    name: how_it_works
    from_schema: http://example.org/aopwiki-emod
    alias: how_it_works
    owner: KeRelationship
    domain_of:
    - Event
    - KeRelationship
    range: string
  biological_plausibility:
    name: biological_plausibility
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: biological_plausibility
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  empirical_support:
    name: empirical_support
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: empirical_support
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  uncertainties:
    name: uncertainties
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: uncertainties
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  quantitative_understanding:
    name: quantitative_understanding
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: quantitative_understanding
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  taxon_evidence:
    name: taxon_evidence
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: taxon_evidence
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  weight_of_evidence:
    name: weight_of_evidence
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: weight_of_evidence
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  response_relationship:
    name: response_relationship
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: response_relationship
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  time_scale:
    name: time_scale
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: time_scale
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  modulating_factors:
    name: modulating_factors
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: modulating_factors
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  known_loops:
    name: known_loops
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: known_loops
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  evidence_collection_strategy:
    name: evidence_collection_strategy
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: evidence_collection_strategy
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: string
  references:
    name: references
    from_schema: http://example.org/aopwiki-emod
    alias: references
    owner: KeRelationship
    domain_of:
    - Event
    - KeRelationship
    range: string
  completion_score:
    name: completion_score
    from_schema: http://example.org/aopwiki-emod
    alias: completion_score
    owner: KeRelationship
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: float
  has_tabulated_evidence:
    name: has_tabulated_evidence
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: has_tabulated_evidence
    owner: KeRelationship
    domain_of:
    - KeRelationship
    range: boolean
  assays:
    name: assays
    description: Assays that measure both the upstream and the downstream Event of
      this relationship in the same test system, so that one assay can inform the
      relationship as a single module.
    from_schema: http://example.org/aopwiki-emod
    alias: assays
    owner: KeRelationship
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Citation
    - BioTargetFamily
    - TestGuideline
    range: Assay
    multivalued: true
  aops:
    name: aops
    from_schema: http://example.org/aopwiki-emod
    alias: aops
    owner: KeRelationship
    domain_of:
    - Event
    - KeRelationship
    - Assay
    - Stressor
    range: AopToKeRelationship
    multivalued: true
    inlined: true
    inlined_as_list: true
  taxons:
    name: taxons
    from_schema: http://example.org/aopwiki-emod
    alias: taxons
    owner: KeRelationship
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: KeRelationshipToTaxon
    multivalued: true
    inlined: true
    inlined_as_list: true
  sexes:
    name: sexes
    from_schema: http://example.org/aopwiki-emod
    alias: sexes
    owner: KeRelationship
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: KeRelationshipToSex
    multivalued: true
    inlined: true
    inlined_as_list: true
  life_stages:
    name: life_stages
    from_schema: http://example.org/aopwiki-emod
    alias: life_stages
    owner: KeRelationship
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: KeRelationshipToLifeStage
    multivalued: true
    inlined: true
    inlined_as_list: true
  created_at:
    name: created_at
    description: Timestamp of when the record was created
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: created_at
    owner: KeRelationship
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Assay
    - Observation
    - Evidence
    - Stressor
    - Citation
    - BiologicalAction
    - BiologicalObject
    - BiologicalProcess
    - LevelOfBiologicalOrganization
    - AopToEvent
    - AopToLifeStage
    - AopToKeRelationship
    - AopToSex
    - AopToPrototypicalStressor
    - AopToTaxon
    - AssignedLicense
    - BioTargetFamily
    - CellTerm
    - ConfidenceLevel
    - Directness
    - EventToLifeStage
    - EventToSex
    - EventToTaxon
    - ExperimentSetup
    - ExperimentType
    - Handbook
    - HarmonizedAop
    - HarmonizedEvent
    - License
    - LifeStageTerm
    - OecdStatus
    - OrganTerm
    - KeRelationshipToLifeStage
    - KeRelationshipToSex
    - KeRelationshipToTaxon
    - SexTerm
    - EventComponent
    - TaxonTerm
    - TestGuideline
    range: datetime
  updated_at:
    name: updated_at
    description: Timestamp of when the record was last updated
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: updated_at
    owner: KeRelationship
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Assay
    - Observation
    - Evidence
    - Stressor
    - Citation
    - BiologicalAction
    - BiologicalObject
    - BiologicalProcess
    - LevelOfBiologicalOrganization
    - AopToEvent
    - AopToLifeStage
    - AopToKeRelationship
    - AopToSex
    - AopToPrototypicalStressor
    - AopToTaxon
    - AssignedLicense
    - BioTargetFamily
    - CellTerm
    - ConfidenceLevel
    - Directness
    - EventToLifeStage
    - EventToSex
    - EventToTaxon
    - ExperimentSetup
    - ExperimentType
    - Handbook
    - HarmonizedAop
    - HarmonizedEvent
    - License
    - LifeStageTerm
    - OecdStatus
    - OrganTerm
    - KeRelationshipToLifeStage
    - KeRelationshipToSex
    - KeRelationshipToTaxon
    - SexTerm
    - EventComponent
    - TaxonTerm
    - TestGuideline
    range: datetime