Class: Event

An Event is a measurable biological change at a defined level of biological organization, described in the abstract so that it can be measured and supported by evidence. An Event may be described in the AOP-Wiki before it is used anywhere, and becomes a Key Event when it is incorporated into an Adverse Outcome Pathway. The AOP-Wiki defines a Key Event as "a change in biological or physiological state that is both measurable and essential to the progression of a defined biological perturbation leading to a specific adverse outcome." Within a pathway, the Key Events at the starting and ending positions are Molecular Initiating Events and Adverse Outcomes, and those between them are intermediate Key Events. These positions are recorded per pathway and rest on the mechanistic evidence available to the authors of that pathway, so one Event may serve as a Molecular Initiating Event in one Adverse Outcome Pathway and as an intermediate Key Event in another.

__

Whether an Event's change can be measured experimentally depends on factors such as the level of biological organization and the species. Molecular and cellular changes can be tested and measured in model organisms in a laboratory context. Changes up to the population level can be observed in model organisms in a lab and in ecological indicator species. Changes at the individual or population level in humans are observed through epidemiological and clinical studies rather than tested.

__

An Event is a type of change rather than a particular occurrence of one, and is therefore not an exposure event in an open system: the exposure of a population to a pollutant in air or water is not an Event. Such real-world exposures can rarely be observed at the molecular level, so the Molecular Initiating Event that follows one is not usually observable at the time of the exposure event. Describing Events in the abstract keeps supporting evidence separate from what is inferred.

URI: http://example.org/aopwiki-emod/Event

classDiagram class Event click Event href "../Event/" Event : aop_oecd_endorsed_count Event : aop_oecd_program_count Event : aop_open_for_adoption_count Event : aops Event --> "*" AopToEvent : aops click AopToEvent href "../AopToEvent/" Event : assays Event --> "*" Assay : assays click Assay href "../Assay/" Event : bio_target_families Event --> "*" BioTargetFamily : bio_target_families click BioTargetFamily href "../BioTargetFamily/" Event : biological_organization_id Event --> "0..1" LevelOfBiologicalOrganization : biological_organization_id click LevelOfBiologicalOrganization href "../LevelOfBiologicalOrganization/" Event : cell_term_id Event --> "0..1" CellTerm : cell_term_id click CellTerm href "../CellTerm/" Event : completion_score Event : created_at Event : definition Event : event_components Event --> "*" EventComponent : event_components click EventComponent href "../EventComponent/" Event : evidence_for_chemical_initiation Event : examples_using_ao Event : has_method_text Event : how_it_works Event : id Event : integration_score Event : life_stages Event --> "*" EventToLifeStage : life_stages click EventToLifeStage href "../EventToLifeStage/" Event : measured_or_detected Event : observations Event --> "*" Observation : observations click Observation href "../Observation/" Event : organ_term_id Event --> "0..1" OrganTerm : organ_term_id click OrganTerm href "../OrganTerm/" Event : references Event : sexes Event --> "*" EventToSex : sexes click EventToSex href "../EventToSex/" Event : short_name Event : supporting_tax_evidence Event : taxons Event --> "*" EventToTaxon : taxons click EventToTaxon href "../EventToTaxon/" Event : test_guidelines Event --> "*" TestGuideline : test_guidelines click TestGuideline href "../TestGuideline/" Event : title Event : updated_at

Slots

Name	Cardinality and Range	Description	Inheritance
created_at	0..1 Datetime	Timestamp of when the record was created	direct
updated_at	0..1 Datetime	Timestamp of when the record was last updated	direct
id	1 Integer		direct
title	0..1 String	A descriptive phrase which defines a discrete biological change that can be m...	direct
short_name	0..1 String	A reasonable abbreviation of the Key Event title, used in labelling throughou...	direct
biological_organization_id	0..1 LevelOfBiologicalOrganization	The level of biological organization at which the Key Event occurs (e	direct
how_it_works	0..1 String	The mechanistic basis explaining how perturbation of this Key Event leads to ...	direct
measured_or_detected	0..1 String	A description of the type(s) of measurements that can be employed to evaluate...	direct
supporting_tax_evidence	0..1 String	Evidence describing the taxonomic applicability of the Key Event, using Latin...	direct
evidence_for_chemical_initiation	0..1 String	Documentation of how specific prototypical stressors (generally chemicals) ca...	direct
examples_using_ao	0..1 String	Examples illustrating the regulatory significance of this Key Event when it s...	direct
references	0..1 String	Literature cited in support of this Key Event description	direct
definition	0..1 String	A description of the biological state being observed or measured, the biologi...	direct
organ_term_id	0..1 OrganTerm	The organ or tissue in which the Key Event takes place	direct
cell_term_id	0..1 CellTerm	The cell type in which the Key Event takes place	direct
completion_score	0..1 Float	Calculated metric indicating how complete the Key Event documentation is	direct
integration_score	0..1 Float	Calculated metric for integration and priority assessment of the Key Event	direct
has_method_text	0..1 String	Indicates whether method text has been provided for this Key Event	direct
aop_open_for_adoption_count	0..1 Integer		direct
aop_oecd_program_count	0..1 Integer		direct
aop_oecd_endorsed_count	0..1 Integer		direct
event_components	* EventComponent		direct
assays	* Assay		direct
observations	* Observation		direct
bio_target_families	* BioTargetFamily		direct
test_guidelines	* TestGuideline		direct
aops	* AopToEvent		direct
life_stages	* EventToLifeStage		direct
sexes	* EventToSex		direct
taxons	* EventToTaxon		direct

Usages

used by	used in	type	used
KeRelationship	upstream_event_id	range	Event
KeRelationship	downstream_event_id	range	Event
Assay	events	range	Event
Observation	events	range	Event
AopToEvent	event_id	range	Event
BioTargetFamily	events	range	Event
EventToLifeStage	event_id	range	Event
EventToSex	event_id	range	Event
EventToTaxon	event_id	range	Event
HarmonizedEvent	source_event_id	range	Event
HarmonizedEvent	harmonized_event_id	range	Event
TestGuideline	events	range	Event

Identifier and Mapping Information

Schema Source

from schema: http://example.org/aopwiki-emod

Mappings

Mapping Type	Mapped Value
self	http://example.org/aopwiki-emod/Event
native	http://example.org/aopwiki-emod/Event

LinkML Source

Direct

name: Event
description: 'An Event is a measurable biological change at a defined level of biological
  organization, described in the abstract so that it can be measured and supported
  by evidence. An Event may be described in the AOP-Wiki before it is used anywhere,
  and becomes a Key Event when it is incorporated into an Adverse Outcome Pathway.
  The AOP-Wiki defines a Key Event as "a change in biological or physiological state
  that is both measurable and essential to the progression of a defined biological
  perturbation leading to a specific adverse outcome." Within a pathway, the Key Events
  at the starting and ending positions are Molecular Initiating Events and Adverse
  Outcomes, and those between them are intermediate Key Events. These positions are
  recorded per pathway and rest on the mechanistic evidence available to the authors
  of that pathway, so one Event may serve as a Molecular Initiating Event in one Adverse
  Outcome Pathway and as an intermediate Key Event in another.


  Whether an Event''s change can be measured experimentally depends on factors such
  as the level of biological organization and the species. Molecular and cellular
  changes can be tested and measured in model organisms in a laboratory context. Changes
  up to the population level can be observed in model organisms in a lab and in ecological
  indicator species. Changes at the individual or population level in humans are observed
  through epidemiological and clinical studies rather than tested.


  An Event is a type of change rather than a particular occurrence of one, and is
  therefore not an exposure event in an open system: the exposure of a population
  to a pollutant in air or water is not an Event. Such real-world exposures can rarely
  be observed at the molecular level, so the Molecular Initiating Event that follows
  one is not usually observable at the time of the exposure event. Describing Events
  in the abstract keeps supporting evidence separate from what is inferred.'
from_schema: http://example.org/aopwiki-emod
slots:
- created_at
- updated_at
attributes:
  id:
    name: id
    from_schema: http://example.org/aopwiki-emod
    identifier: true
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Assay
    - Observation
    - Evidence
    - Stressor
    - Citation
    - BiologicalAction
    - BiologicalObject
    - BiologicalProcess
    - LevelOfBiologicalOrganization
    - AopToEvent
    - AopToLifeStage
    - AopToKeRelationship
    - AopToSex
    - AopToPrototypicalStressor
    - AopToTaxon
    - AssignedLicense
    - BioTargetFamily
    - CellTerm
    - ConfidenceLevel
    - Directness
    - EventToLifeStage
    - EventToSex
    - EventToTaxon
    - ExperimentSetup
    - ExperimentType
    - Handbook
    - HarmonizedAop
    - HarmonizedEvent
    - License
    - LifeStageTerm
    - OecdStatus
    - OrganTerm
    - KeRelationshipToLifeStage
    - KeRelationshipToSex
    - KeRelationshipToTaxon
    - SexTerm
    - EventComponent
    - TaxonTerm
    - TestGuideline
    - User
    range: integer
    required: true
  title:
    name: title
    description: A descriptive phrase which defines a discrete biological change that
      can be measured.
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - Assay
    - Citation
  short_name:
    name: short_name
    description: A reasonable abbreviation of the Key Event title, used in labelling
      throughout AOP-Wiki.
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
  biological_organization_id:
    name: biological_organization_id
    description: The level of biological organization at which the Key Event occurs
      (e.g., molecular, cellular, tissue, organ, organism).
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    range: LevelOfBiologicalOrganization
    inlined: true
  how_it_works:
    name: how_it_works
    description: The mechanistic basis explaining how perturbation of this Key Event
      leads to downstream effects.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    - KeRelationship
  measured_or_detected:
    name: measured_or_detected
    description: A description of the type(s) of measurements that can be employed
      to evaluate the Key Event and the relative level of scientific confidence in
      those measurements.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
  supporting_tax_evidence:
    name: supporting_tax_evidence
    description: Evidence describing the taxonomic applicability of the Key Event,
      using Latin or common names of species or broader taxonomic groupings.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
  evidence_for_chemical_initiation:
    name: evidence_for_chemical_initiation
    description: Documentation of how specific prototypical stressors (generally chemicals)
      can trigger or perturb this Key Event.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
  examples_using_ao:
    name: examples_using_ao
    description: Examples illustrating the regulatory significance of this Key Event
      when it serves as an adverse outcome.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
  references:
    name: references
    description: Literature cited in support of this Key Event description.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    - KeRelationship
  definition:
    name: definition
    description: A description of the biological state being observed or measured,
      the biological compartment in which it is measured, and its general role in
      the biology.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
  organ_term_id:
    name: organ_term_id
    description: The organ or tissue in which the Key Event takes place.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    range: OrganTerm
    inlined: true
  cell_term_id:
    name: cell_term_id
    description: The cell type in which the Key Event takes place.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    range: CellTerm
    inlined: true
  completion_score:
    name: completion_score
    description: Calculated metric indicating how complete the Key Event documentation
      is.
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: float
  integration_score:
    name: integration_score
    description: Calculated metric for integration and priority assessment of the
      Key Event.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    range: float
  has_method_text:
    name: has_method_text
    description: Indicates whether method text has been provided for this Key Event.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
  aop_open_for_adoption_count:
    name: aop_open_for_adoption_count
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    range: integer
  aop_oecd_program_count:
    name: aop_oecd_program_count
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    range: integer
  aop_oecd_endorsed_count:
    name: aop_oecd_endorsed_count
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    range: integer
  event_components:
    name: event_components
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    range: EventComponent
    multivalued: true
    inlined: true
    inlined_as_list: true
  assays:
    name: assays
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Citation
    - BioTargetFamily
    - TestGuideline
    range: Assay
    multivalued: true
  observations:
    name: observations
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    - Citation
    range: Observation
    multivalued: true
  bio_target_families:
    name: bio_target_families
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    - Assay
    - Citation
    range: BioTargetFamily
    multivalued: true
  test_guidelines:
    name: test_guidelines
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    - Assay
    range: TestGuideline
    multivalued: true
  aops:
    name: aops
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    domain_of:
    - Event
    - KeRelationship
    - Assay
    - Stressor
    range: AopToEvent
    multivalued: true
    inlined: true
    inlined_as_list: true
  life_stages:
    name: life_stages
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: EventToLifeStage
    multivalued: true
    inlined: true
    inlined_as_list: true
  sexes:
    name: sexes
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: EventToSex
    multivalued: true
    inlined: true
    inlined_as_list: true
  taxons:
    name: taxons
    from_schema: http://example.org/aopwiki-emod
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: EventToTaxon
    multivalued: true
    inlined: true
    inlined_as_list: true

Induced

name: Event
description: 'An Event is a measurable biological change at a defined level of biological
  organization, described in the abstract so that it can be measured and supported
  by evidence. An Event may be described in the AOP-Wiki before it is used anywhere,
  and becomes a Key Event when it is incorporated into an Adverse Outcome Pathway.
  The AOP-Wiki defines a Key Event as "a change in biological or physiological state
  that is both measurable and essential to the progression of a defined biological
  perturbation leading to a specific adverse outcome." Within a pathway, the Key Events
  at the starting and ending positions are Molecular Initiating Events and Adverse
  Outcomes, and those between them are intermediate Key Events. These positions are
  recorded per pathway and rest on the mechanistic evidence available to the authors
  of that pathway, so one Event may serve as a Molecular Initiating Event in one Adverse
  Outcome Pathway and as an intermediate Key Event in another.


  Whether an Event''s change can be measured experimentally depends on factors such
  as the level of biological organization and the species. Molecular and cellular
  changes can be tested and measured in model organisms in a laboratory context. Changes
  up to the population level can be observed in model organisms in a lab and in ecological
  indicator species. Changes at the individual or population level in humans are observed
  through epidemiological and clinical studies rather than tested.


  An Event is a type of change rather than a particular occurrence of one, and is
  therefore not an exposure event in an open system: the exposure of a population
  to a pollutant in air or water is not an Event. Such real-world exposures can rarely
  be observed at the molecular level, so the Molecular Initiating Event that follows
  one is not usually observable at the time of the exposure event. Describing Events
  in the abstract keeps supporting evidence separate from what is inferred.'
from_schema: http://example.org/aopwiki-emod
attributes:
  id:
    name: id
    from_schema: http://example.org/aopwiki-emod
    identifier: true
    alias: id
    owner: Event
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Assay
    - Observation
    - Evidence
    - Stressor
    - Citation
    - BiologicalAction
    - BiologicalObject
    - BiologicalProcess
    - LevelOfBiologicalOrganization
    - AopToEvent
    - AopToLifeStage
    - AopToKeRelationship
    - AopToSex
    - AopToPrototypicalStressor
    - AopToTaxon
    - AssignedLicense
    - BioTargetFamily
    - CellTerm
    - ConfidenceLevel
    - Directness
    - EventToLifeStage
    - EventToSex
    - EventToTaxon
    - ExperimentSetup
    - ExperimentType
    - Handbook
    - HarmonizedAop
    - HarmonizedEvent
    - License
    - LifeStageTerm
    - OecdStatus
    - OrganTerm
    - KeRelationshipToLifeStage
    - KeRelationshipToSex
    - KeRelationshipToTaxon
    - SexTerm
    - EventComponent
    - TaxonTerm
    - TestGuideline
    - User
    range: integer
    required: true
  title:
    name: title
    description: A descriptive phrase which defines a discrete biological change that
      can be measured.
    from_schema: http://example.org/aopwiki-emod
    alias: title
    owner: Event
    domain_of:
    - Aop
    - Event
    - Assay
    - Citation
    range: string
  short_name:
    name: short_name
    description: A reasonable abbreviation of the Key Event title, used in labelling
      throughout AOP-Wiki.
    from_schema: http://example.org/aopwiki-emod
    alias: short_name
    owner: Event
    domain_of:
    - Aop
    - Event
    range: string
  biological_organization_id:
    name: biological_organization_id
    description: The level of biological organization at which the Key Event occurs
      (e.g., molecular, cellular, tissue, organ, organism).
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: biological_organization_id
    owner: Event
    domain_of:
    - Event
    range: LevelOfBiologicalOrganization
    inlined: true
  how_it_works:
    name: how_it_works
    description: The mechanistic basis explaining how perturbation of this Key Event
      leads to downstream effects.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: how_it_works
    owner: Event
    domain_of:
    - Event
    - KeRelationship
    range: string
  measured_or_detected:
    name: measured_or_detected
    description: A description of the type(s) of measurements that can be employed
      to evaluate the Key Event and the relative level of scientific confidence in
      those measurements.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: measured_or_detected
    owner: Event
    domain_of:
    - Event
    range: string
  supporting_tax_evidence:
    name: supporting_tax_evidence
    description: Evidence describing the taxonomic applicability of the Key Event,
      using Latin or common names of species or broader taxonomic groupings.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: supporting_tax_evidence
    owner: Event
    domain_of:
    - Event
    range: string
  evidence_for_chemical_initiation:
    name: evidence_for_chemical_initiation
    description: Documentation of how specific prototypical stressors (generally chemicals)
      can trigger or perturb this Key Event.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: evidence_for_chemical_initiation
    owner: Event
    domain_of:
    - Event
    range: string
  examples_using_ao:
    name: examples_using_ao
    description: Examples illustrating the regulatory significance of this Key Event
      when it serves as an adverse outcome.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: examples_using_ao
    owner: Event
    domain_of:
    - Event
    range: string
  references:
    name: references
    description: Literature cited in support of this Key Event description.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: references
    owner: Event
    domain_of:
    - Event
    - KeRelationship
    range: string
  definition:
    name: definition
    description: A description of the biological state being observed or measured,
      the biological compartment in which it is measured, and its general role in
      the biology.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: definition
    owner: Event
    domain_of:
    - Event
    range: string
  organ_term_id:
    name: organ_term_id
    description: The organ or tissue in which the Key Event takes place.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: organ_term_id
    owner: Event
    domain_of:
    - Event
    range: OrganTerm
    inlined: true
  cell_term_id:
    name: cell_term_id
    description: The cell type in which the Key Event takes place.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: cell_term_id
    owner: Event
    domain_of:
    - Event
    range: CellTerm
    inlined: true
  completion_score:
    name: completion_score
    description: Calculated metric indicating how complete the Key Event documentation
      is.
    from_schema: http://example.org/aopwiki-emod
    alias: completion_score
    owner: Event
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: float
  integration_score:
    name: integration_score
    description: Calculated metric for integration and priority assessment of the
      Key Event.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: integration_score
    owner: Event
    domain_of:
    - Event
    range: float
  has_method_text:
    name: has_method_text
    description: Indicates whether method text has been provided for this Key Event.
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: has_method_text
    owner: Event
    domain_of:
    - Event
    range: string
  aop_open_for_adoption_count:
    name: aop_open_for_adoption_count
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: aop_open_for_adoption_count
    owner: Event
    domain_of:
    - Event
    range: integer
  aop_oecd_program_count:
    name: aop_oecd_program_count
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: aop_oecd_program_count
    owner: Event
    domain_of:
    - Event
    range: integer
  aop_oecd_endorsed_count:
    name: aop_oecd_endorsed_count
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: aop_oecd_endorsed_count
    owner: Event
    domain_of:
    - Event
    range: integer
  event_components:
    name: event_components
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: event_components
    owner: Event
    domain_of:
    - Event
    range: EventComponent
    multivalued: true
    inlined: true
    inlined_as_list: true
  assays:
    name: assays
    from_schema: http://example.org/aopwiki-emod
    alias: assays
    owner: Event
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Citation
    - BioTargetFamily
    - TestGuideline
    range: Assay
    multivalued: true
  observations:
    name: observations
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: observations
    owner: Event
    domain_of:
    - Event
    - Citation
    range: Observation
    multivalued: true
  bio_target_families:
    name: bio_target_families
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: bio_target_families
    owner: Event
    domain_of:
    - Event
    - Assay
    - Citation
    range: BioTargetFamily
    multivalued: true
  test_guidelines:
    name: test_guidelines
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: test_guidelines
    owner: Event
    domain_of:
    - Event
    - Assay
    range: TestGuideline
    multivalued: true
  aops:
    name: aops
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: aops
    owner: Event
    domain_of:
    - Event
    - KeRelationship
    - Assay
    - Stressor
    range: AopToEvent
    multivalued: true
    inlined: true
    inlined_as_list: true
  life_stages:
    name: life_stages
    from_schema: http://example.org/aopwiki-emod
    alias: life_stages
    owner: Event
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: EventToLifeStage
    multivalued: true
    inlined: true
    inlined_as_list: true
  sexes:
    name: sexes
    from_schema: http://example.org/aopwiki-emod
    alias: sexes
    owner: Event
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: EventToSex
    multivalued: true
    inlined: true
    inlined_as_list: true
  taxons:
    name: taxons
    from_schema: http://example.org/aopwiki-emod
    alias: taxons
    owner: Event
    domain_of:
    - Aop
    - Event
    - KeRelationship
    range: EventToTaxon
    multivalued: true
    inlined: true
    inlined_as_list: true
  created_at:
    name: created_at
    description: Timestamp of when the record was created
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: created_at
    owner: Event
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Assay
    - Observation
    - Evidence
    - Stressor
    - Citation
    - BiologicalAction
    - BiologicalObject
    - BiologicalProcess
    - LevelOfBiologicalOrganization
    - AopToEvent
    - AopToLifeStage
    - AopToKeRelationship
    - AopToSex
    - AopToPrototypicalStressor
    - AopToTaxon
    - AssignedLicense
    - BioTargetFamily
    - CellTerm
    - ConfidenceLevel
    - Directness
    - EventToLifeStage
    - EventToSex
    - EventToTaxon
    - ExperimentSetup
    - ExperimentType
    - Handbook
    - HarmonizedAop
    - HarmonizedEvent
    - License
    - LifeStageTerm
    - OecdStatus
    - OrganTerm
    - KeRelationshipToLifeStage
    - KeRelationshipToSex
    - KeRelationshipToTaxon
    - SexTerm
    - EventComponent
    - TaxonTerm
    - TestGuideline
    range: datetime
  updated_at:
    name: updated_at
    description: Timestamp of when the record was last updated
    from_schema: http://example.org/aopwiki-emod
    rank: 1000
    alias: updated_at
    owner: Event
    domain_of:
    - Aop
    - Event
    - KeRelationship
    - Assay
    - Observation
    - Evidence
    - Stressor
    - Citation
    - BiologicalAction
    - BiologicalObject
    - BiologicalProcess
    - LevelOfBiologicalOrganization
    - AopToEvent
    - AopToLifeStage
    - AopToKeRelationship
    - AopToSex
    - AopToPrototypicalStressor
    - AopToTaxon
    - AssignedLicense
    - BioTargetFamily
    - CellTerm
    - ConfidenceLevel
    - Directness
    - EventToLifeStage
    - EventToSex
    - EventToTaxon
    - ExperimentSetup
    - ExperimentType
    - Handbook
    - HarmonizedAop
    - HarmonizedEvent
    - License
    - LifeStageTerm
    - OecdStatus
    - OrganTerm
    - KeRelationshipToLifeStage
    - KeRelationshipToSex
    - KeRelationshipToTaxon
    - SexTerm
    - EventComponent
    - TaxonTerm
    - TestGuideline
    range: datetime