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Class: ASLOutput

Measurement results from an airway surface liquid assay. Contains the measured values for ASL height, periciliary layer depth, and ion composition.

URI: soma:ASLOutput

 classDiagram
    class ASLOutput
    click ASLOutput href "../ASLOutput/"
      AssayOutputMeasurement <|-- ASLOutput
        click AssayOutputMeasurement href "../AssayOutputMeasurement/"

      ASLOutput : asl_height_um





        ASLOutput --> "0..1" QuantityValue : asl_height_um
        click QuantityValue href "../QuantityValue/"



      ASLOutput : asl_ph





        ASLOutput --> "0..1" QuantityValue : asl_ph
        click QuantityValue href "../QuantityValue/"



      ASLOutput : data_in_figure_only

      ASLOutput : description

      ASLOutput : evidence





        ASLOutput --> "* _recommended_" EvidenceItem : evidence
        click EvidenceItem href "../EvidenceItem/"



      ASLOutput : experimental_group





        ASLOutput --> "0..1" ExperimentalGroupEnum : experimental_group
        click ExperimentalGroupEnum href "../ExperimentalGroupEnum/"



      ASLOutput : id

      ASLOutput : ion_composition

      ASLOutput : measured_under





        ASLOutput --> "0..1" ExposureCondition : measured_under
        click ExposureCondition href "../ExposureCondition/"



      ASLOutput : mucus_layer_thickness





        ASLOutput --> "0..1" QuantityValue : mucus_layer_thickness
        click QuantityValue href "../QuantityValue/"



      ASLOutput : name

      ASLOutput : periciliary_layer_depth





        ASLOutput --> "0..1" QuantityValue : periciliary_layer_depth
        click QuantityValue href "../QuantityValue/"




Inheritance

Slots

Name Cardinality and Range Description Inheritance
asl_height_um 0..1
QuantityValue
Airway surface liquid height in micrometers direct
periciliary_layer_depth 0..1
QuantityValue
Depth of the periciliary layer in micrometers direct
mucus_layer_thickness 0..1
QuantityValue
Thickness of the mucus gel layer in micrometers direct
ion_composition 0..1
String
Ionic composition (Cl-, Na+, K+) direct
asl_ph 0..1
QuantityValue
pH of airway surface liquid direct
evidence * recommended
EvidenceItem
Evidence items backing this object's claims AssayOutputMeasurement
experimental_group 0..1
ExperimentalGroupEnum
The role of this output record's group in the experimental design: control, v... AssayOutputMeasurement
measured_under 0..1
ExposureCondition
Reference (by id) to the specific ExposureCondition this output record was me... AssayOutputMeasurement
data_in_figure_only 0..1
Boolean
True when the quantitative values for this output record are reported only in... AssayOutputMeasurement
id 1
Uriorcurie
A unique identifier for the entity NamedThing
name 0..1
String
A human-readable name for the entity NamedThing
description 0..1
String
A detailed description of the entity NamedThing

Usages

used by used in type used
ASLAssay has_specified_output range ASLOutput

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/EHS-Data-Standards/soma

Mappings

Mapping Type Mapped Value
self soma:ASLOutput
native soma:ASLOutput

LinkML Source

Direct

name: ASLOutput
description: Measurement results from an airway surface liquid assay. Contains the
  measured values for ASL height, periciliary layer depth, and ion composition.
from_schema: https://w3id.org/EHS-Data-Standards/soma
is_a: AssayOutputMeasurement
slots:
- asl_height_um
- periciliary_layer_depth
- mucus_layer_thickness
- ion_composition
- asl_ph

Induced

name: ASLOutput
description: Measurement results from an airway surface liquid assay. Contains the
  measured values for ASL height, periciliary layer depth, and ion composition.
from_schema: https://w3id.org/EHS-Data-Standards/soma
is_a: AssayOutputMeasurement
attributes:
  asl_height_um:
    name: asl_height_um
    description: Airway surface liquid height in micrometers. TIER 1 - primary measurement
      for ASL assays.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: asl_height_um
    owner: ASLOutput
    domain_of:
    - ASLOutput
    range: QuantityValue
    inlined: true
  periciliary_layer_depth:
    name: periciliary_layer_depth
    description: Depth of the periciliary layer in micrometers. TIER 1 - helps give
      confidence to the outcome.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: periciliary_layer_depth
    owner: ASLOutput
    domain_of:
    - ASLOutput
    range: QuantityValue
    inlined: true
  mucus_layer_thickness:
    name: mucus_layer_thickness
    description: Thickness of the mucus gel layer in micrometers. TIER 2.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: mucus_layer_thickness
    owner: ASLOutput
    domain_of:
    - ASLOutput
    - MucociliaryClearanceOutput
    range: QuantityValue
    inlined: true
  ion_composition:
    name: ion_composition
    description: Ionic composition (Cl-, Na+, K+). TIER 3 - not critical for comparison
      but relevant for mechanism.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: ion_composition
    owner: ASLOutput
    domain_of:
    - ASLOutput
    range: string
  asl_ph:
    name: asl_ph
    description: pH of airway surface liquid. TIER 3.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: asl_ph
    owner: ASLOutput
    domain_of:
    - ASLOutput
    range: QuantityValue
    inlined: true
  evidence:
    name: evidence
    description: Evidence items backing this object's claims. Each one carries an
      exact quote from a cited publication.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: evidence
    owner: ASLOutput
    domain_of:
    - KeyEvent
    - KeyEventRelationship
    - Assay
    - AssayOutputMeasurement
    range: EvidenceItem
    recommended: true
    multivalued: true
    inlined: true
    inlined_as_list: true
  experimental_group:
    name: experimental_group
    description: 'The role of this output record''s group in the experimental design:
      control, vehicle control, baseline, treated, recovery, or sham. Lets extraction
      distinguish the control/baseline response from the treated response so a change
      relative to control can be assembled downstream.'
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: experimental_group
    owner: ASLOutput
    domain_of:
    - AssayOutputMeasurement
    range: ExperimentalGroupEnum
  measured_under:
    name: measured_under
    description: Reference (by id) to the specific ExposureCondition this output record
      was measured under. Links each set of response values to the concentration/treatment
      it corresponds to, so a dose-response series keeps each response paired with
      its exposure level. The referenced condition should be listed in the assay's
      has_exposure_condition.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: measured_under
    owner: ASLOutput
    domain_of:
    - AssayOutputMeasurement
    range: ExposureCondition
    inlined: false
  data_in_figure_only:
    name: data_in_figure_only
    description: True when the quantitative values for this output record are reported
      only in a figure or chart and could not be read from the text. The record then
      documents that the endpoint was measured and where its data lives (via an evidence
      item's figure_reference and article_section), without numeric values. This keeps
      figure-only results visible to reviewers in the workbook instead of silently
      dropping them.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: data_in_figure_only
    owner: ASLOutput
    domain_of:
    - AssayOutputMeasurement
    range: boolean
  id:
    name: id
    description: A unique identifier for the entity.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    identifier: true
    alias: id
    owner: ASLOutput
    domain_of:
    - NamedThing
    - Unit
    - NamedEntity
    range: uriorcurie
    required: true
  name:
    name: name
    description: A human-readable name for the entity.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    slot_uri: schema:name
    alias: name
    owner: ASLOutput
    domain_of:
    - NamedThing
    - Unit
    - NamedEntity
    range: string
  description:
    name: description
    description: A detailed description of the entity.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    slot_uri: schema:description
    alias: description
    owner: ASLOutput
    domain_of:
    - NamedThing
    range: string