Class: GobletCellOutput

name: GobletCellOutput
description: Measurement results from a goblet cell assay. Contains the measured values
  for goblet cell counts, mucin expression, and mucus properties.
from_schema: https://w3id.org/EHS-Data-Standards/soma
is_a: AssayOutputMeasurement
slots:
- goblet_cell_count
- goblet_cell_percentage
- muc5ac_mrna_expression
- muc5ac_protein_expression
- muc5b_mrna_expression
- muc5b_protein_expression
- muc5ac_muc5b_ratio
- mucin_protein_concentration
- mucin_secretion_rate
- percent_solids
- goblet_to_ciliated_ratio
- mucus_viscosity

name: GobletCellOutput
description: Measurement results from a goblet cell assay. Contains the measured values
  for goblet cell counts, mucin expression, and mucus properties.
from_schema: https://w3id.org/EHS-Data-Standards/soma
is_a: AssayOutputMeasurement
attributes:
  goblet_cell_count:
    name: goblet_cell_count
    description: Number of goblet cells (raw count). TIER 1 - want both raw and relative
      information.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: goblet_cell_count
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  goblet_cell_percentage:
    name: goblet_cell_percentage
    description: Percentage of goblet cells. TIER 1.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: goblet_cell_percentage
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  muc5ac_mrna_expression:
    name: muc5ac_mrna_expression
    description: MUC5AC mRNA expression level (fold change). TIER 1.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: muc5ac_mrna_expression
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  muc5ac_protein_expression:
    name: muc5ac_protein_expression
    description: MUC5AC protein expression level. TIER 1.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: muc5ac_protein_expression
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  muc5b_mrna_expression:
    name: muc5b_mrna_expression
    description: MUC5B mRNA expression level (fold change). TIER 1.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: muc5b_mrna_expression
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  muc5b_protein_expression:
    name: muc5b_protein_expression
    description: MUC5B protein expression level. TIER 1.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: muc5b_protein_expression
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  muc5ac_muc5b_ratio:
    name: muc5ac_muc5b_ratio
    description: MUC5AC to MUC5B ratio. TIER 1 - important for disease state.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: muc5ac_muc5b_ratio
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  mucin_protein_concentration:
    name: mucin_protein_concentration
    description: Total mucin protein concentration. TIER 1 - want both direct and
      comparative measures.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: mucin_protein_concentration
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  mucin_secretion_rate:
    name: mucin_secretion_rate
    description: Mucin secretion rate. TIER 1.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: mucin_secretion_rate
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  percent_solids:
    name: percent_solids
    description: Percent solids in apical secretion (overall secretion). TIER 1.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: percent_solids
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  goblet_to_ciliated_ratio:
    name: goblet_to_ciliated_ratio
    description: Ratio of goblet cells to ciliated cells. TIER 2 - related to transdifferentiation
      but not critical for outcome.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: goblet_to_ciliated_ratio
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  mucus_viscosity:
    name: mucus_viscosity
    description: Mucus viscosity in centipoise. TIER 2.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: mucus_viscosity
    owner: GobletCellOutput
    domain_of:
    - GobletCellOutput
    range: QuantityValue
    inlined: true
  evidence:
    name: evidence
    description: Evidence items backing this object's claims. Each one carries an
      exact quote from a cited publication.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: evidence
    owner: GobletCellOutput
    domain_of:
    - KeyEvent
    - KeyEventRelationship
    - Assay
    - AssayOutputMeasurement
    range: EvidenceItem
    recommended: true
    multivalued: true
    inlined: true
    inlined_as_list: true
  experimental_group:
    name: experimental_group
    description: 'The role of this output record''s group in the experimental design:
      control, vehicle control, baseline, treated, recovery, or sham. Lets extraction
      distinguish the control/baseline response from the treated response so a change
      relative to control can be assembled downstream.'
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: experimental_group
    owner: GobletCellOutput
    domain_of:
    - AssayOutputMeasurement
    range: ExperimentalGroupEnum
  measured_under:
    name: measured_under
    description: Reference (by id) to the specific ExposureCondition this output record
      was measured under. Links each set of response values to the concentration/treatment
      it corresponds to, so a dose-response series keeps each response paired with
      its exposure level. The referenced condition should be listed in the assay's
      has_exposure_condition.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: measured_under
    owner: GobletCellOutput
    domain_of:
    - AssayOutputMeasurement
    range: ExposureCondition
    inlined: false
  data_in_figure_only:
    name: data_in_figure_only
    description: True when the quantitative values for this output record are reported
      only in a figure or chart and could not be read from the text. The record then
      documents that the endpoint was measured and where its data lives (via an evidence
      item's figure_reference and article_section), without numeric values. This keeps
      figure-only results visible to reviewers in the workbook instead of silently
      dropping them.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    alias: data_in_figure_only
    owner: GobletCellOutput
    domain_of:
    - AssayOutputMeasurement
    range: boolean
  id:
    name: id
    description: A unique identifier for the entity.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    identifier: true
    alias: id
    owner: GobletCellOutput
    domain_of:
    - NamedThing
    - Unit
    - NamedEntity
    range: uriorcurie
    required: true
  name:
    name: name
    description: A human-readable name for the entity.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    slot_uri: schema:name
    alias: name
    owner: GobletCellOutput
    domain_of:
    - NamedThing
    - Unit
    - NamedEntity
    range: string
  description:
    name: description
    description: A detailed description of the entity.
    from_schema: https://w3id.org/EHS-Data-Standards/soma
    rank: 1000
    slot_uri: schema:description
    alias: description
    owner: GobletCellOutput
    domain_of:
    - NamedThing
    range: string